John Love, Ph.D.
Pronouns: John
Associate Professor of Biochemistry
San Diego
Primary Email: [email protected]
Phone/Fax
Primary Phone: 41616
Building/Location
5500 Campanile Dr
San Diego,
CA
92182
Mail Code: Links
Bio
The overall focus of the research conducted in my lab is protein design and engineering. Our initial engineering goal is to redesign, mutate and drive small proteins to self-assemble into complexes of specific structure (e.g. precise dimer formation). The small proteins will then be redesigned to bind to specific regions of target proteins expressed by pathogenic organisms. These design targets are geared towards applications in the field of protein-based drug design. Our approach entails a design cycle which couples computer science, molecular biology, biochemistry and spectroscopy. This cyclic approach ultimately increases our understanding of the forces that drive protein self-assembly and raises the likelihood of successful protein-protein complex design. We do this using a combination of computational chemistry, molecular biology, biochemistry and spectroscopy.
Areas of Specialization
Biochemistry, Computational Chemistry, Molecular Biology, Biochemistry, Spectroscopy